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The power of the

brain-gut connection

The power of the

brain-gut connection

The communication system between your brain and your gut is called the gut-brain axis.1 If you’ve ever felt the sensation of butterflies in your stomach, lost your appetite when under stress, or made a decision based on a “gut feeling,” you’ve experienced the strength of the connection between your brain and your gut.

IBS CAN BE CAUSED BY MISCOMMUNICATION

Your brain and gut are interconnected via a complex network of nerves and chemical signals. And while they are in constant, two-way communication—that communication can sometimes break down. If you have IBS, it may mean that your brain and your gut aren’t “talking” to one another the way they should. This can result in your brain sending signals to your gut that cause uncomfortable symptoms, including pain.2

How does this happen? Some people have overly sensitive nerves in their gut that fire in response to normal signals, like digesting a meal or moving gas through the intestines. Although barely noticeable for most people, normal sensations like these can cause severe pain for patients with IBS.3

RESTORING BRAIN-GUT COMMUNICATION

What’s the true impact of IBS?

In one study, most people said they would give up

10-15 years

of their lives for an instant cure for their IBS.5

For nearly 40 years, gut-directed hypnotherapy has been used to treat the symptoms of IBS.4 The relaxation, focus, and pleasant feelings you experience during

gut-directed hypnotherapy can help bring your mind and your gut back into alignment by helping your brain learn how to filter out the pain and uncomfortable sensations you feel in your gut.2

Restoring Brain-Gut Communication

RESTORING
BRAIN-GUT COMMUNICATION

For nearly 40 years, gut-directed hypnotherapy has been used to treat the symptoms of IBS.4 The relaxation, focus, and pleasant feelings you experience during gut-directed hypnotherapy can

help bring your mind and your gut back into alignment by helping your brain learn how to filter out the pain and uncomfortable sensations you feel in your gut.2

Restoring Brain-Gut Communication
What’s the true impact of IBS?

In one study, most people said they would give up

10-15 years

of their lives for an instant cure for their IBS.5

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References:

  1. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interaction between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015;28(2):203-209.
  2. The Rome Foundation. Brain-Gut Psychotherapy Referral Guide. Accessed August 15, 2022. https://theromefoundation.org/wp-content/uploads/Rome-Foundation_GastroPsych-referral-project.pdf
  3. Kinsinger S. How Your Brain and Emotions Control Your Gut. Accessed September 2, 2022. https://www.loyolamedicine.org/about-us/blog/how-your-brain-and-emotions-control-your-gut
  4. Donnet AS, Hasan SS, Whorwell PJ. Hypnotherapy for irritable bowel syndrome: patient expectations and perceptions. Therap Adv Gastroenterol. 2022;15:17562848221074208.
  5. Lacy BE, Pimentel M, Brenner DM, et al. ACG Clinical Guideline: Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2021;116(1):17-44.
  6. International Foundation for Gastrointestinal Disorders. What is IBS? Accessed August 15, 2022. https://aboutibs.org/what-is-ibs/facts-about-ibs/
  7. Miller V, Carruthers HR, Morris J, Hasan SS, Archbold S, Whorwell PJ. Hypnotherapy for irritable bowel syndrome: an audit of one thousand adult patients. Aliment Pharmacol Ther. 2015;41(9):844-855.

IMPORTANT INFORMATION

Regulora® is a prescription-only digital therapeutic device intended to provide behavioral therapy through gut-directed hypnotherapy for adults 22 years of age and older who have been diagnosed with irritable bowel syndrome (IBS). Regulora is indicated as a 3-month treatment for patients with abdominal pain due to IBS and is intended to be used together with other IBS treatments.

US federal law restricts this mobile application device to sale by or on the order of a physician. Regulora is intended for patients who speak and read English. Regulora may not be appropriate for patients with mental or physical impairment that would prevent interacting with a mobile video application. Regulora may not be appropriate for patients with evidence of intestinal illness that better explains IBS symptoms such as celiac disease or inflammatory bowel disease. Regulora should not be used in lieu of your current IBS medication or therapy. In a clinical trial of Regulora, side effects were low. About 1% of patients experienced abdominal pain, constipation, fatigue, or headache which was thought to be related to using Regulora.